How long will it take for the therapy to begin working?

That depends on what therapy is best for you. Injections are the easiest to manage and titrate. The creams and gels are a little more difficult to determine absorption rates. Regardless of the therapy that best fits you it will depend on a number of factors. How severe is your condition? Do you have other medical factors that could contribute to challenges in therapy? What is your body fat percentage? Testosterone is a lipophylic, meaning it is absorbed through fat tissue in the body. Increased body fat could slow absorption. Most patients see improvement by week 4 of therapy with some getting near immediate results. If no improvement is experienced by week 12 the diagnosis should be reconsidered and alternatives should be explored.